What distinguishes high-level programming languages from low-level languages?

High-level programming languages are designed to be more user-friendly, which is reflected in their syntax and structure. They often resemble human language or mathematical notation, making them easier to read and write for programmers. This abstraction allows developers to focus on problem-solving and algorithm development rather than dealing with the complex details of the machine's hardware.

In contrast, low-level languages, such as assembly or machine code, require a deeper understanding of the computer's architecture. They are more difficult to work with because programmers must manage memory and CPU instructions directly. This complexity can make development more error-prone and time-consuming.

Thus, the ease of use, readability, and maintainability of high-level languages are key factors that distinguish them from low-level languages, making option B the most accurate characterization.